Backbone Assignment of the N-terminal Domain of Human Replication Protein A 70 kDa
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Replication Protein A (RPA) is the eukaryotic single-stranded DNA binding protein. It involves in DNA replication, repair, and damage response. Among three subunits, RPA70 has a protein-protein binding domain (RPA70N) at the N-terminal. It has known that the domain recruits several damage response proteins to the damaged site. Also, it is suggested that there are more candidates that interact with RPA70N. Even though several studies performed on the structural aspects of RPA70N and its ligand binding, the backbone assignments of RPA70N is not available in public. In this study, we present the backbone assignments of RPA70N.
Abstract
Replication Protein A (RPA) is the eukaryotic single-stranded DNA binding protein. It involves in DNA replication, repair, and damage response. Among three subunits, RPA70 has a protein-protein binding domain (RPA70N) at the N-terminal. It has known that the domain recruits several damage response proteins to the damaged site. Also, it is suggested that there are more candidates that interact with RPA70N. Even though several studies performed on the structural aspects of RPA70N and its ligand binding, the backbone assignments of RPA70N is not available in public. In this study, we present the backbone assignments of RPA70N.
참고문헌 (17)
- M. S. Wold, , Proc. Natl. Acad. Sci. U. S. A, 85, pp.2523~ (1988)
- P. Bulet, , Immunol. Rev, 198, pp.169~ (2004)
- M. S. Wold, , Annu. Rev. Biochem, 66, pp.61~ (1997)
- A. Bochkarev, , Nature, 385, pp.176~ (1997)
- 김민규, "NMR Study of Temperature-Dependent Single-Stranded DNA Binding Affinity of Human Replication Protein A", Journal of the Korean Magnetic Resonance Society, 20(3), pp.66~70 (2016), 한국자기공명학회[DOI]
- A. Dutta, , Nature, 365, pp.79~ (1993)
- X. Xu, , Mol. Cell. Biol, 28, pp.7345~ (2008)
- B. Ning, , PLoS One, 10, pp.e0116093~ (2016)
- H. L. Ball, , Mol. Cell. Biol, 27, pp.3367~ (2007)
- D. M. Jacobs, , J. Biomol. NMR, 14, pp.321~ (1999)
- E. Bochkareva, , Proc. Natl. Acad. Sci. U. S. A, 43, pp.15412~ (2005)
- M. D. Feldkamp, , Biochemistry, 52, pp.6515~ (2013)
- N. S. Gavande, , Pharmacol. Therapeut, 160, pp.65~ (2016)
- E. M. Souza-Fagundes, , Anal. Biochem, 421, pp.742~ (2012)
- 이고은, "1H, 15N, and 13C backbone assignments and secondary structure of the cytoplasmic domainA of mannitol trasporter IIMannitol from Thermoanaerobacter Tencongensis phosphotransferase system", Journal of the Korean Magnetic Resonance Society, 19(1), pp.42~48 (2015), 한국자기공명학회[DOI]
- T. D. Goddard, "SPARKY 3" (2008), University of California
- Y. Shen, , J. Biomol. NMR, 44, pp.213~ (2009)