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불안 감소를 위한 생기능자기조절 훈련(뉴로피드백) 임상연구: 체계적 문헌고찰

Neurofeedback Training for Anxiety: A Systematic Review

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Objectives: The purpose of this systematic review was to investigate the clinical effects of neurofeed-back training on reducing anxiety.Methods: Eight databases were used to extract clinical reports on neurofeedback intervention for anxi-ety reduction published until 2016. We analyzed the characteristics of selected studies and evaluated biases using the Risk of Bias (RoB) assessment.Results: A total of 22 clinical trials were extracted for the analysis. The risk of bias in most studies was high or unclear. The Chinese Classification of Mental Disorders-3 (CCMD-3) was the most frequently used diagnostic criteria, the Hamilton Rating Scale for Anxiety (HAMA) was the most frequently used assessment tool, and the alpha wave activity increase, sensorimotor rhythm (SMR), and theta wave training were the most frequently used intervention methods. All papers showed a statistically sig-nificant decrease of anxiety symptoms; however, significant adverse events were not reported.Conclusions: Neurofeedback intervention might be beneficial for reducing anxiety. However, the qual-ity of the studies used in the analysis was low, and the heterogeneity of the population and inter-ventions was revealed. Therefore, more scientifically designed clinical studies regarding neurofeed-back training are required.

Abstract

Objectives: The purpose of this systematic review was to investigate the clinical effects of neurofeed-back training on reducing anxiety.Methods: Eight databases were used to extract clinical reports on neurofeedback intervention for anxi-ety reduction published until 2016. We analyzed the characteristics of selected studies and evaluated biases using the Risk of Bias (RoB) assessment.Results: A total of 22 clinical trials were extracted for the analysis. The risk of bias in most studies was high or unclear. The Chinese Classification of Mental Disorders-3 (CCMD-3) was the most frequently used diagnostic criteria, the Hamilton Rating Scale for Anxiety (HAMA) was the most frequently used assessment tool, and the alpha wave activity increase, sensorimotor rhythm (SMR), and theta wave training were the most frequently used intervention methods. All papers showed a statistically sig-nificant decrease of anxiety symptoms; however, significant adverse events were not reported.Conclusions: Neurofeedback intervention might be beneficial for reducing anxiety. However, the qual-ity of the studies used in the analysis was low, and the heterogeneity of the population and inter-ventions was revealed. Therefore, more scientifically designed clinical studies regarding neurofeed-back training are required.

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