神枕이 치매유발백서의 학습을 통한 기억에 미치는 영향
An Experimental Study on the Effect of Sinchim on Enhancing of memory in Rat with water maze
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Objectives : This study was performed to examine the effect of Sinchim on enhancing of memory in rat with water maze. Methods : Experimental animals(white rat) were classfied into normal, control, and aroma sample group. Then, they were injected β-amyloid into control and aroma sample group rat's brain about 5μl to injure its brain. After rat smelt Sinchim about 12days, I did water maze test and anatomized its hippocampus. Sections were cut coronally at 30 μm.(X100) Results : 1. In acquisition test of water maze learning, β-amyloid injured group took more time than normal group to reach the escape platform noticeably and through the session of trial, Sinchim aroma sample group shortened time than β-amyloid injured group after 6 days. 2. In the acetyltransferase(AchE) immunostained method, it was shown that Sinchim aroma sample recovered the synthesis of ChATCholoneacetyltransferase). Conclusion : Smelling Sinchim would be useful for enhancing of memory.
Abstract
Objectives : This study was performed to examine the effect of Sinchim on enhancing of memory in rat with water maze. Methods : Experimental animals(white rat) were classfied into normal, control, and aroma sample group. Then, they were injected β-amyloid into control and aroma sample group rat's brain about 5μl to injure its brain. After rat smelt Sinchim about 12days, I did water maze test and anatomized its hippocampus. Sections were cut coronally at 30 μm.(X100) Results : 1. In acquisition test of water maze learning, β-amyloid injured group took more time than normal group to reach the escape platform noticeably and through the session of trial, Sinchim aroma sample group shortened time than β-amyloid injured group after 6 days. 2. In the acetyltransferase(AchE) immunostained method, it was shown that Sinchim aroma sample recovered the synthesis of ChATCholoneacetyltransferase). Conclusion : Smelling Sinchim would be useful for enhancing of memory.
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