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본태성 진전에 대한 중의학 연구동향

A Review on Treatment of Essential Tremor in Traditional Chinese Medicine

김상호|이승환|임정화|신아리|배영롱|임재유
대한한방신경정신과학회 (The Korean Society Of Oriental Neuropsychiatry)|2017.06|동의신경정신과학회지 (The Korean Society of Oriental Neuropsychiatry)|제28권 제2호|pp. 95-107

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참고문헌

키워드

Traditional Chinese Medicine.Essential TremorIdiopathic Tremor
주제분류한의학

초록

Objectives: This study was performed to review studies on Essential Tremor (ET) in Traditional Chinese medicine (TCM).Methods: We reviewed papers in the China National Knowledge Infrastructure (CNKI) from 2007∼2016. Search keywords were 原发性震颤, 特发性震颤, essential tremor and idiopathic tremor, and excluded non-clinical studies, non-related to ET or TCM studies, theses for degrees and non-Randomized Controlled Trial (RCT). The quality of the articles was assessed by Jadad scale and the Risk of Bias (RoB).Results: Thirteen studies were selected. ‘Criteria for the diagnosis of ET’ was most frequently used as diagnostic criteria. ‘Tremor rating scale’ was primarily used for outcome measurement. Meta-analysis of nine trials revealed the effective rate of acupuncture and Western medicine (WM+Acu) groups was significantly higher compared to the WM group (RR: 1.48, 95 percent CI: 1.20 to 1.82, p=0.0002, I2=0 percent) and tremor rating scale was also significantly decreased in the treatment group (MD: −1.35, 95 percent CI: −2.17 to −0.54, p=0.001, I2=0 percent). Also, effective rates of Electro-acupuncture (EA) and Chinese herbal medicine (CHM) groups were significantly higher than that of the WM group {(RR: 1.53, 95 percent CI: 1.22 to 1.92, p=0.0003, I2=0 percent) in EA vs. WM and (RR: 1.35, 95 percent CI: 1.16 to 1.57, p＜0.0001, I2=0 percent) in CHM vs. WM}. However, the quality of selected clinical studies was poor.Conclusions: Treatment of ET in TCM may be more effective and safe than in Western medicine. Therefore, we hope this study will lead to further clinical research on treatment of ET in Korean medicine.

Abstract

Objectives: This study was performed to review studies on Essential Tremor (ET) in Traditional Chinese medicine (TCM).Methods: We reviewed papers in the China National Knowledge Infrastructure (CNKI) from 2007∼2016. Search keywords were 原发性震颤, 特发性震颤, essential tremor and idiopathic tremor, and excluded non-clinical studies, non-related to ET or TCM studies, theses for degrees and non-Randomized Controlled Trial (RCT). The quality of the articles was assessed by Jadad scale and the Risk of Bias (RoB).Results: Thirteen studies were selected. ‘Criteria for the diagnosis of ET’ was most frequently used as diagnostic criteria. ‘Tremor rating scale’ was primarily used for outcome measurement. Meta-analysis of nine trials revealed the effective rate of acupuncture and Western medicine (WM+Acu) groups was significantly higher compared to the WM group (RR: 1.48, 95 percent CI: 1.20 to 1.82, p=0.0002, I2=0 percent) and tremor rating scale was also significantly decreased in the treatment group (MD: −1.35, 95 percent CI: −2.17 to −0.54, p=0.001, I2=0 percent). Also, effective rates of Electro-acupuncture (EA) and Chinese herbal medicine (CHM) groups were significantly higher than that of the WM group {(RR: 1.53, 95 percent CI: 1.22 to 1.92, p=0.0003, I2=0 percent) in EA vs. WM and (RR: 1.35, 95 percent CI: 1.16 to 1.57, p＜0.0001, I2=0 percent) in CHM vs. WM}. However, the quality of selected clinical studies was poor.Conclusions: Treatment of ET in TCM may be more effective and safe than in Western medicine. Therefore, we hope this study will lead to further clinical research on treatment of ET in Korean medicine.

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