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알코올 사용장애의 한약치료 연구동향

Current Research Trends of Traditional Herbal Medicine for Alcohol Use Disorder

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주제분류한의학

초록

Objectives: To review clinical research trends of herbal medicine treatment for alcohol use disorder. Methods: Three domestic databases and eight foreign databases were used to search for published articles by November 1, 2023 in each database. A total of 9 studies were included. Results: There were eight randomized control studies and one non-randomized control study. All randomized control studies were designed with 2-arm paralleled. The non-randomized control study was designed with 2-arm crossover. The most commonly used prescriptions were Kudzu extract capsules and Seoganhaeul capsules. The most used herbs were Puerariae Radix, Hyperici Perforati Herba, and Acanthopanacis Senticosi Radix et Rhizoma seu Caulis. Conclusions: Traditional herbal medicine might be effective in alleviating drinking behavior, physical problems, and psychological problems of patients with alcohol use disorder. However, the limited number of included studies suggests that further methodologically rigorous research studies on herbal medicine treatment for alcohol use disorder are needed in the future.

Abstract

Objectives: To review clinical research trends of herbal medicine treatment for alcohol use disorder. Methods: Three domestic databases and eight foreign databases were used to search for published articles by November 1, 2023 in each database. A total of 9 studies were included. Results: There were eight randomized control studies and one non-randomized control study. All randomized control studies were designed with 2-arm paralleled. The non-randomized control study was designed with 2-arm crossover. The most commonly used prescriptions were Kudzu extract capsules and Seoganhaeul capsules. The most used herbs were Puerariae Radix, Hyperici Perforati Herba, and Acanthopanacis Senticosi Radix et Rhizoma seu Caulis. Conclusions: Traditional herbal medicine might be effective in alleviating drinking behavior, physical problems, and psychological problems of patients with alcohol use disorder. However, the limited number of included studies suggests that further methodologically rigorous research studies on herbal medicine treatment for alcohol use disorder are needed in the future.

참고문헌 (55)

  1. American Psychiatric Association, "Diagnosticand statistical manual of mental disorders: DSM-5", pp.537~551 (2013), American Psychiatric Association
  2. Rehm J, "Global Burden of Disease and the Impact of Mental and Addictive Disorders", Curr Psychiatry Rep, 21, pp.10~ (2019)
  3. Global status report on alcohol and health 2018, "Vladimir P", World health organization, ~ (2018)
  4. The epidemiological survey of mental disorders in Korea 2021, "Korean Ministry of Health and Welfare", Korean Ministry of Health and Welfare, ~ (2021)
  5. Diagnosticand statistical manual of mental disorders Text Revision: DSM-5-TR, "American Psychiatric Association", American Psychiatric Association, 613~ (2022)
  6. 김진숙, "생애사연구를 통해 본 남성 알코올 중독자의 회복 경험", 생명연구, 52, pp.201~223 (2019), 생명문화연구소[DOI]
  7. 조용혁, "자살과 알코올 사용장애를 동반한 기분장애와의 연관성: 공통 데이터 모델을 활용한 연구", 신경정신의학, 60(3), pp.232~239 (2021), 대한신경정신의학회[DOI]
  8. Beigel A, "Planning for the development of comprehensive community alcoholism services : I. The prevalence survey", Am J Psychiatry, 131, pp.1112~1116 (1974)
  9. Mullahy J, "Employment, unemployment, and problem drinking", Journal of Health Economics, (15), pp.409~434 (1996)
  10. Min SG, "The latest psychiatry", pp.543~554 (2015), Ilzogak
  11. 조근호, "정신건강의학과 외래에서 알코올사용장애 환자 치료", 신경정신의학, 58(3), pp.159~166 (2019), 대한신경정신의학회[DOI]
  12. Lee GS, "Treatment of Alcohol Use Disorder", The Journal of Korean Diabetes, 13, pp.85~90 (2012)
  13. Korean Academy of Addiction Psychiatry, "Addiction Psychiatry", pp.196~200 (2019)
  14. Mekonen T, "Treatment rates for alcohol use disorders : a systematic review and meta-analysis", Addiction, 116, pp.2617~2634 (2021)
  15. 조맹제, "한국 정신장애의 역학 조사 연구(I) : 각 정신장애의 유병률", 신경정신의학, 43(4), pp.470~480 (2004), 대한신경정신의학회
  16. The Textbook Compilation Committee of Neuropsychiatry of Korean Medical Schools in Nation, "2018 Korean society of oriental neuropsychiatry", pp.338~339 (2018), Maver
  17. Chen P, "Acupuncture for alcohol use disorder", Int J Physiol Pathophysiol Pharmacol, 10, pp.60~69 (2018)
  18. Na Young Shin, "Acupuncture for Alcohol Use Disorder: A Meta-Analysis", Evidence-Based Complementary and Alternative Medicine, 2017, pp.1~6 (2017), Hindawi Limited[DOI]
  19. Chen H, "Acupoint stimulation for alcohol use disorder : A systematic review and meta-analysis", Medicine(Baltimore), 102, pp.e32614~ (2023)
  20. Park JH, "Clinical Review of Alcoholism Treatment Using Auricular acupuncture and Traditional herbal medication", The Journal of East-west medicines, 21, pp.1~15 (1996)
  21. Yang FJ, "Research progress of traditional Chinese medicine on alcohol dependence treatment", Chinese Journal of Drug Dependence, 30, pp.332~337 (2021)
  22. Shebek J, "A pilot study exploring the effect of Kudzu root on the drinking habits of patients with chronic alcoholism", The journal of alternative and complementary medicine, 6, pp.45~48 (2000)
  23. Lukas SE, "An extract of the Chinese herbal root Kudzu reduces alcohol drinking by heavy drinkers in a naturalistic setting", Alcoholism:clinical and experimental research, 29, pp.56~62
  24. Cao GY, "A Comparative study on the treatment of alcohol dependence by traditional Chinese medicine Jiedu decoction and furazolidone", Herbi medical J, 28, pp.1196~1197 (2007)
  25. Chang JH, "Application of Hugan Capsule in Alcohol Dependence Patients", Chinese Community Doctors, 35(13), pp.85~ (2011)
  26. Lukas SE, "A Standardized Kudzu Extract (NPI-031)Reduces Alcohol Consumption in Non Treatment-Seeking Male Heavy Drinkers", Psychopharmacology, 226, pp.65~73 (2013)
  27. Wang ZB, "Influence of modified Chaihu Plus Longgu Muli Tang on quality of life in patients with alcohol dependence", Modern Chinese Clinical Medicine, 21, pp.33~35 (2014)
  28. Yin XF, "Comparison between Shugan Jieyu Capsule and Diazepam Tablets in Treatment of Alcohol Dependence Syndrome with Anxiety", Chinese Journal of Rural Medicine and Pharmacy, 26, pp.37~38 (2019)
  29. Liu H, "Effect of Shugan Jieyu Capsule on Alcohol Dependence Depression and Anxiety Symptoms", Chinese journal of clinical rational drug use, 13, pp.100~101 (2020)
  30. Qin JF, "Curative effect of Shugan Jieyu Capsules combined with family therapy on alcohol dependence syndrome", Journal of hubei of Chinese medicine, 25, pp.107~109 (2023)
  31. The Textbook Compilation Committee of herbal medicine of Korean Medical Schools in Nation, "Herbal medicine", pp.184~ (2020), Younglimsa
  32. Wang S, "A comprehensive review on Pueraria: Insights on its chemistry and medicinal value", Biomed Pharmacother, 131 (2020)
  33. Keung WM, "Kudzu root : an ancient Chinese source of modern antidipsotropic agents", Phytochemistry, 47, pp.499~506 (1998)
  34. Keung WM, "Biogenic aldehyde(s)derived from the action of monoamine oxidase may mediate the antidipsotropic effect of daidzin", Chemico-biological interactions, 130, pp.919~930 (2001)
  35. Zhou YX, "Puerarin : a review of pharmacological effects", Phytother Res, 28, pp.961~975 (2014)
  36. Ashok K. Singh, "Kudzu Root Extract Suppresses Voluntary Alcohol Intake and Alcohol Withdrawal Symptoms in P Rats Receiving Free Access to Water and Alcohol", Journal of Medicinal Food, 7(2), pp.168~179 (2004), 한국식품영양과학회
  37. Peng JH, "Puerarin ameliorates experimental alcoholic liver injury by inhibition of endotoxin gut leakage, Kupffer cell activation, and endotoxin receptors expression", J Pharmacol Exp Ther, 344, pp.646~654 (2013)
  38. Bian H, "Study on the autophagy-related mechanism of puerarin in improving the cognitive impairment induced by alcohol in female mice", Brain Inj, 36, pp.137~145 (2022)
  39. 김범회, "알콜로 유도된 흰쥐의 근위축에서 葛根의 보호 작용과 그 기전에 대한 고찰", 한방재활의학과학회지, 27(2), pp.1~8 (2017), 한방재활의학과학회
  40. Song SG, "The effects of Galwhahaejung-tang administration and physical exercise on chronic alcoholic absorption of white mice: changes of the CYP2E1 in the hepatic microsome and transaminases GOT,GPT", Journal of oriental rehabilitation medicine, 11, pp.205~ (2001)
  41. Ministry of food and drug safety, "Publication of English Version of National Standard of Traditional Medicinal (Herbal and Botanical) Materials" (2013), biohub
  42. "Korean Pharmacopoeia" (2023)[URL]
  43. Chinese pharmacopoeia commission, "Pharmacopoeia of the People’s Republic of China" (2015), Beijing
  44. Le TT, "Herb-drug Interactions in Neuropsychiatric Pharmacotherapy-A Review of Clinically Relevant Findings", Curr Neuropharmacol, 20, pp.1736~1751 (2022)
  45. Rezvani AH, "Attenuation of alcohol intake by extract of Hypericum perforatum(St. John’s Wort)in two different strains of alcohol-preferring rats", Alcohol Alcohol, 34, pp.699~705 (1999)
  46. 최성훈, "Methanolic extract from the root of Bupleuri falcatum L. attenuates cocaine-induced c-Fos expression in rat brain.", 한국한의학연구원논문집, 16(1), pp.141~147 (2010), 한국한의학연구원
  47. Yoon SS, "Effect of saikosaponin A on maintenance of intravenous morphine self-administration", Neurosci Lett, 529, pp.97~101 (2012)
  48. Yoon SS, "Effects of saikosaponin A on cocaine self-administration in rats", Neurosci Lett, 555, pp.198~202 (2013)
  49. Deng XX, "Simultaneous LC–MS Quantification of 15 Lignans in Schisandra chinensis (Turcz.) Baill", Fruit. Chromatographia, 67, pp.559~566 (2008)
  50. 한찬규, "오미자농축액이 급성주정중독량 및 장기간 주정을 투여한 흰쥐의 혈중 알코올 분해율과 간 기능 보호에 미치는 영향", 한국식품영양과학회지, 43(8), pp.1139~1147 (2014), 한국식품영양과학회
  51. Selzer ML, "The Michigan alcoholism screening test : the quest for a new diagnostic instrument", Am J Psychiatry, 127, pp.1653~1658 (1971)
  52. Kim KB, "The preliminary study of the Korean alcoholism screening test(III)", J Korean Neuropsychiatr Assoc, 30, pp.569~581 (1991)
  53. Mayfield D, "The CAGE questionnaire : validation of a new alcoholism screening instrument", Am J Psychiatry, 131, pp.1121~1123 (1974)
  54. Cherpitel CJ, "A brief screening instrument for problem drinking in the emergency room: the RAPS4. Rapid Alcohol Problems Screen", J Stud Alcohol, 61, pp.447~449 (2000)
  55. Saunders JB, "Development of the Alcohol Use Disorders Identification Test(AUDIT) : WHO Collaborative Project on Early Detection of Persons with Harmful Alcohol Consumption—II", Addiction, 88, pp.791~804 (1993)

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