초산모에서 산모 연령과 임신합병증과의 관련성 연구
Association between Maternal Age and Complications of Pregnancy in Primipara
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Objectives: The purpose of this study was to analyze the association between maternal age and pregnancy outcome in primipara. Methods: We evalu- ated retrospectively the clinical characteristics and pregnancy outcomes in primiparous mothers who delivered a fetus after more than 22 weeks of ges- tation in I hospital from January 2017 to December 2018. Statistical analysis was performed using chi-square tests and multivariable logistic regression. The education, occupation, abortion history, assisted reproductive technology (ART) and multiple pregnancy all showed significantly higher incidence, depending on maternal age (p < 0.000). Results: The odds ratio in maternal complications was 2.327 times higher in mothers 40 years and above than mothers 29 years and below, and 1.912 times higher in mothers 35-39 years than mothers 29 years and below. The odds ratio in gestational diabetes was 3.337 times higher in mothers 40 years and above than mothers 29 years and below, and 2.698 times higher in mothers 35-39 years than mothers 29 years and below. Conclusions: Consequently, this study showed a significant association between maternal age and pregnancy outcome in primipara. How- ever, as the maternal age increases, the improvement of socioeconomic status and health level are expected to have a greater impact on outcome of pregnancy despite the physical defects of biological aging.
Abstract
Objectives: The purpose of this study was to analyze the association between maternal age and pregnancy outcome in primipara. Methods: We evalu- ated retrospectively the clinical characteristics and pregnancy outcomes in primiparous mothers who delivered a fetus after more than 22 weeks of ges- tation in I hospital from January 2017 to December 2018. Statistical analysis was performed using chi-square tests and multivariable logistic regression. The education, occupation, abortion history, assisted reproductive technology (ART) and multiple pregnancy all showed significantly higher incidence, depending on maternal age (p < 0.000). Results: The odds ratio in maternal complications was 2.327 times higher in mothers 40 years and above than mothers 29 years and below, and 1.912 times higher in mothers 35-39 years than mothers 29 years and below. The odds ratio in gestational diabetes was 3.337 times higher in mothers 40 years and above than mothers 29 years and below, and 2.698 times higher in mothers 35-39 years than mothers 29 years and below. Conclusions: Consequently, this study showed a significant association between maternal age and pregnancy outcome in primipara. How- ever, as the maternal age increases, the improvement of socioeconomic status and health level are expected to have a greater impact on outcome of pregnancy despite the physical defects of biological aging.
참고문헌 (22)
- "Population census, average age at first marriage"[URL]
- Attali E, "The impact of advanced maternal age on pregnancy outcome", Best Pract Res Clinl Obstet Gynaecol, 70, pp.2~9 (2021)[DOI]
- 황종윤, "모자 보건의료서비스 종사자를 위한 고위험 임신 및 합병증 임신 분류", 한국모자보건학회지, 24(2), pp.65~74 (2020), 한국모자보건학회[DOI]
- 조기현, "고연령 산모에서 태어난 신생아의 출생 체중: 분포와 특징", Perinatology, 25(4), pp.276~283 (2014), 대한주산의학회
- Ogawa K, "Association between very advanced maternal age and adverse pregnancy outcomes : a cross sectional Japanese study", BMC Pregnancy Childbirth, 17, pp.349~ (2017)
- Kil KC, "A clinical review of the perinatal prognosis of pregnant women aged 40 years and older", Proceeding of the Korean Society of Obstetrics and Gynecology, pp.177~ (2006)
- 박상화, "40세 이상 고령 출산과 임신결과에 관한 연구", 대한보건연구, 39(2), pp.31~38 (2013), 사단법인 대한보건협회[DOI]
- 김태은, "건강한 고령 초산모에서 산모 연령이 임신결과에 미치는 영향", Perinatology, 20(2), pp.146~152 (2009), 대한주산의학회
- 최원일, "30대 초반 산모의 임신과 출산에 관한 연구", Obstetrics & Gynecology Science, 48(9), pp.2073~2079 (2005), 대한산부인과학회
- Lee KH, "A consideration of the pregnancy outcome in elderly primipara", Obstet Gynecol Sci, 37(10), pp.1967~1973 (1994)
- 박희진, "35세 이상 고령 산모의 산과적 예후", Obstetrics & Gynecology Science, 49(10), pp.2066~2074 (2006), 대한산부인과학회
- Park SK, "Lifestyle habits and pregnancy rates of infertile patients who underwent assisted reproductive surgery", Proceeding of the Korean Society of Obstetrics and Gynecology, pp.166~ (2009)
- Kwon HY, "Management of pregnancy by assisted reproductive technology", Proceeding of the Korean Society of Obstetrics and Gynecology, pp.141~144 (2017)
- 허혁, "35세 이상 고령산모의 임신과 출산에 대한 임상적 연구", Obstetrics & Gynecology Science, 47(3), pp.458~463 (2004), 대한산부인과학회
- 양정보, "전자간증의 위험인자에 대한 임상적 연구", Obstetrics & Gynecology Science, 47(12), pp.2325~2332 (2004), 대한산부인과학회
- Ahn GH., "Prevention and treatment of preeclampsia", Proceeding of the Korean Society of Obstetrics and Gynecology, pp.96~102 (2018)
- An SH., "The Relation between Late childbearing after age 35 and Neonatal Status, morbidity", pp.2017
- 이민경, "분만여성과 배우자의 출산연령이 산모와 신생아 합병증에 미치는 영향", 한국간호교육학회지, 18(1), pp.94~100 (2012), 한국간호교육학회[DOI]
- Kim DS, "Impact of delayed childbearing on infant mortality", pp.2019
- 임달오, "혼외 출생아의 조기분만과 저체중아 발생 위험도에 관한 연구: 2008-2012년 출생통계", 보건의료산업학회지, 8(3), pp.137~145 (2014), 보건의료산업학회
- 김윤경, "조기진통 임부의 조산 발생 영향요인: 전향적 코호트 연구", 여성건강간호학회지, 24(3), pp.233~242 (2018), 한국여성건강간호학회[DOI]
- Jang DH, "Maternal age effects on birth weight and low birth weight", Department of Business Administration, pp.2015