연1회 정주용 졸레드론산의 순응도 분석
Analysis of the Adherence in Once Yearly Intravenous Zoledronic Acid
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objectives: We investigated drug adherence of once yearly intravenous bisphosphonate in patients with osteoporosis or osteoporotic fractures, and factors that influence their adherence. Materials and Methods: Patients treated with once yearly intravenous bisphosphonate were asked about drug information and drug adherence using questionnaires. Factors related drug adherence were analyzed between non adherence group and adherence group. Results: 65 patients (49.6%) were adherence group, 66 patients (50.3%) were included in non-adherence group. In group 1, were administered mainly due to ‘after physicians suggestion’ in 22 cases (36.1%) and ‘for ease of administration’ in 17 cases (27.9%). In group 2, the patients were not readministered mainly due to economic reasons in 21 cases (42%), unconcerning to osteoporosis in 14 cases (28%). Conclusions: This study shows ‘doctor's suggestion’ and ‘ease of administration’ could enhance drug adherence.
Abstract
Objectives: We investigated drug adherence of once yearly intravenous bisphosphonate in patients with osteoporosis or osteoporotic fractures, and factors that influence their adherence. Materials and Methods: Patients treated with once yearly intravenous bisphosphonate were asked about drug information and drug adherence using questionnaires. Factors related drug adherence were analyzed between non adherence group and adherence group. Results: 65 patients (49.6%) were adherence group, 66 patients (50.3%) were included in non-adherence group. In group 1, were administered mainly due to ‘after physicians suggestion’ in 22 cases (36.1%) and ‘for ease of administration’ in 17 cases (27.9%). In group 2, the patients were not readministered mainly due to economic reasons in 21 cases (42%), unconcerning to osteoporosis in 14 cases (28%). Conclusions: This study shows ‘doctor's suggestion’ and ‘ease of administration’ could enhance drug adherence.
참고문헌 (10)
- Nanes MS, "Clinical assessment of fracture risk and novel therapeutic strategies to combat osteoporosis", Fertil Steril, 92, pp.403~412 (2009)
- Park HM, "The Use of Osteoporosis Medications in Korea in 2008", Korean Journal of Bone Metabolism, 16, pp.87~93 (2009)
- Imaz I, "Poor bisphosphonate adherence for treatment of osteoporosis increases fracture risk: systematic review and meta-analysis", Osteoporos Int, 21, pp.1943~1951 (2010)
- Haynes RB, "Interventions for enhancing medication adherence", Cochrane Database Syst Rev, 16 (2008)
- Coope J, "Can We Improve Compliance with Long-Term Hrt", Maturitas, 15, pp.151~158 (1992)
- Rees MCP, "The need to improve compliance to HRT", British Journal of Obstetrics and Gynaecology, 104, pp.1~3 (1997)
- Dawson-Hughes B, "A revised clinician's guide to the prevention and treatment of osteoporosis", J Clin Endocrinol Metab, 93, pp.2463~2465 (2008)
- Claxton AJ, "A systematic review of the associations between dose regimens and medication compliance", Clin Ther, 23, pp.1296~1310 (2001)
- Hamilton B, "Tolerability and compliance with risedronate in clinical practice", Osteoporos Int, 14, pp.259~262 (2003)
- Chung JY, "Practice Patterns on Osteoporosis Screening and Treatment at Orthopaedic Surgery Outpatient Unit and the Issue on Different Osteoporosis Treatment Guidelines in Korea", Korean Journal of Bone Metabolism, 15, pp.49~57 (2008)