폐경기간에 따른 골밀도 변화
Change of Bone Mineral Density in Postmenopausal Women According to Their Menopausal Period
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Objectives: To evaluate the associations of the general characteristics and bone mineral density (BMD) of postmenopausal women, and determine the correlation of years since menopause (YSM) at 5-year interval. Methods: A total of 430 postmenopausal women who had visited a university hospital from January 2012 to December 2013 were enrolled in this study. BMD was determined for the lumbar spine and femoral neck by dual-energy X-ray absorptiometry (DXA) using a GE-LUNA Progidy. Pearsons correlation coefficients were made among weight, body mass index (BMI), parity, YSM and BMD. Results: In Pearsons correlation analysis, weight, height and BMI was positively with lumbar BMD (r=0.303, r=0.287, r=0.189, P<0.001). Also, weight, height and BMI was positively with femoral BMD (r=0.244, r=0.225, r=0.156, P<0.001). On the other hand, parity was associated negatively with lumbar and femoral BMD (r=-0.278, r=-0.369, P<0.001). YSM was associated negatively with lumbar and femoral BMD (r=-0.296, r=-0.490, P<0.001). Conclusions: We conclude that although there were several limitations of this study, the results of this study showed that YSM associated with decreased BMD in postmenopausal women. And the BMD of postmenopausal women has influenced by parity, height, weight and BMI.
Abstract
Objectives: To evaluate the associations of the general characteristics and bone mineral density (BMD) of postmenopausal women, and determine the correlation of years since menopause (YSM) at 5-year interval. Methods: A total of 430 postmenopausal women who had visited a university hospital from January 2012 to December 2013 were enrolled in this study. BMD was determined for the lumbar spine and femoral neck by dual-energy X-ray absorptiometry (DXA) using a GE-LUNA Progidy. Pearsons correlation coefficients were made among weight, body mass index (BMI), parity, YSM and BMD. Results: In Pearsons correlation analysis, weight, height and BMI was positively with lumbar BMD (r=0.303, r=0.287, r=0.189, P<0.001). Also, weight, height and BMI was positively with femoral BMD (r=0.244, r=0.225, r=0.156, P<0.001). On the other hand, parity was associated negatively with lumbar and femoral BMD (r=-0.278, r=-0.369, P<0.001). YSM was associated negatively with lumbar and femoral BMD (r=-0.296, r=-0.490, P<0.001). Conclusions: We conclude that although there were several limitations of this study, the results of this study showed that YSM associated with decreased BMD in postmenopausal women. And the BMD of postmenopausal women has influenced by parity, height, weight and BMI.
참고문헌 (18)
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