Factors associated with the decision to undergo risk-reducing salpingo-oophorectomy among women at high risk for hereditary breast and ovarian cancer: a systematic review
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Purpose: This systematic review aims to identify factors associated with risk-reducing salpingo-oophorectomy (RRSO), including the uptake rate and decision timing, among women at high risk for hereditary breast and ovarian cancer (HBOC). Methods: We found 4,935 relevant studies using MEDLINE, Embase, CINAHL, and PsycINFO on July 6, 2020. Two authors screened the articles and extracted data. Twenty-four studies met the inclusion criteria. Quality assessment of articles was conducted using the Risk of Bias for Nonrandomized Studies tool. Results: Five types of factors were identified (demographic factors, clinical factors, family history of cancer, psychological factors, and objective cancer risk). The specific significant factors were older age, having child(ren), being a BRCA1/2 carrier, mastectomy history, perceived risk for ovarian cancer, and perceived advantages of RRSO, whereas objective cancer risk was not significant. The uptake rate of RRSO was 23.4% to 87.2% (mean, 45.2%) among high-risk women for HBOC. The mean time to decide whether to undergo RRSO after BRCA testing was 4 to 34 months. Conclusion: RRSO decisions are affected by demographic, clinical, and psychological factors, rather than objective cancer risk. Nonetheless, women seeking RRSO should be offered information about objective cancer risk. Even though decision-making for RRSO is a complex and multifaceted process, the psychosocial factors that may influence decisions have not been comprehensively examined, including family attitudes toward RRSO, cultural norms, social values, and health care providers’ attitudes.
Abstract
Purpose: This systematic review aims to identify factors associated with risk-reducing salpingo-oophorectomy (RRSO), including the uptake rate and decision timing, among women at high risk for hereditary breast and ovarian cancer (HBOC). Methods: We found 4,935 relevant studies using MEDLINE, Embase, CINAHL, and PsycINFO on July 6, 2020. Two authors screened the articles and extracted data. Twenty-four studies met the inclusion criteria. Quality assessment of articles was conducted using the Risk of Bias for Nonrandomized Studies tool. Results: Five types of factors were identified (demographic factors, clinical factors, family history of cancer, psychological factors, and objective cancer risk). The specific significant factors were older age, having child(ren), being a BRCA1/2 carrier, mastectomy history, perceived risk for ovarian cancer, and perceived advantages of RRSO, whereas objective cancer risk was not significant. The uptake rate of RRSO was 23.4% to 87.2% (mean, 45.2%) among high-risk women for HBOC. The mean time to decide whether to undergo RRSO after BRCA testing was 4 to 34 months. Conclusion: RRSO decisions are affected by demographic, clinical, and psychological factors, rather than objective cancer risk. Nonetheless, women seeking RRSO should be offered information about objective cancer risk. Even though decision-making for RRSO is a complex and multifaceted process, the psychosocial factors that may influence decisions have not been comprehensively examined, including family attitudes toward RRSO, cultural norms, social values, and health care providers’ attitudes.
참고문헌 (40)
- Dan L. Longo, "The Role of Risk-Reducing Surgery in Hereditary Breast and Ovarian Cancer", New England Journal of Medicine, 374(5), pp.454~468 (2016), Massachusetts Medical Society[DOI]
- Nancie Petrucelli, "Hereditary breast and ovarian cancer due to mutations in BRCA1 and BRCA2", Genetics in Medicine, 12(5), pp.245~259 (2010), Springer Science and Business Media LLC[DOI]
- Eunyoung Kang, "The prevalence and spectrum of BRCA1 and BRCA2 mutations in Korean population: recent update of the Korean Hereditary Breast Cancer (KOHBRA) study", Breast Cancer Research and Treatment, 151(1), pp.157~168 (2015), Springer Science and Business Media LLC[DOI]
- Rebbeck TR, "Meta-analysis of risk reduction estimates associated with risk-reducing salpingo-oophorectomy in BRCA1 or BRCA2 mutation carriers", J Natl Cancer Inst, 101(2), pp.80~87 (2009)[DOI]
- Tasleem J. Padamsee, "Decision making for breast cancer prevention among women at elevated risk", Breast Cancer Research, 19(1), pp.34~ (2017), Springer Science and Business Media LLC[DOI]
- Rachel Meadows, "Distinctive psychological and social experiences of women choosing prophylactic oophorectomy for cancer prevention", Health Care for Women International, 39(5), pp.595~616 (2018), Informa UK Limited[DOI]
- A. Fuchsia Howard, "Women’s Decision Making about Risk-Reducing Strategies in the Context of Hereditary Breast and Ovarian Cancer: A Systematic Review", Journal of Genetic Counseling, 18(6), pp.578~597 (2009), Wiley[DOI]
- Martha Hickey, "What information do healthcare professionals need to inform premenopausal women about risk-reducing salpingo-oophorectomy?", Menopause, 27(1), pp.20~25 (2020), Ovid Technologies (Wolters Kluwer Health)[DOI]
- Carol Cherry, "Understanding the Needs of Women Considering Risk-Reducing Salpingo-oophorectomy", Cancer Nursing, 36(3), pp.E33~E38 (2013), Ovid Technologies (Wolters Kluwer Health)[DOI]
- Shoshana M. Rosenberg, "“I don't want to take chances.”: A qualitative exploration of surgical decision making in young breast cancer survivors", Psycho-Oncology, 27(6), pp.1524~1529 (2018), Wiley[DOI]
- Angela R Bradbury, "Uptake and timing of bilateral prophylactic salpingo-oophorectomy among BRCA1 and BRCA2 mutation carriers", Genetics in Medicine, 10(3), pp.161~166 (2008), Springer Science and Business Media LLC[DOI]
- Dongwon Kim, "Factors affecting the decision to undergo risk-reducing salpingo-oophorectomy among women with BRCA gene mutation", Familial Cancer, 12(4), pp.621~628 (2013), Springer Science and Business Media LLC[DOI]
- Krishna Singh, "Impact of family history on choosing risk-reducing surgery among BRCA mutation carriers", American Journal of Obstetrics and Gynecology, 208(4), pp.329.e1~329.e6 (2013), Elsevier BV[DOI]
- Se Ik Kim, "Uptake of risk-reducing salpingo-oophorectomy among female BRCA mutation carriers: experience at the National Cancer Center of Korea", Journal of Cancer Research and Clinical Oncology, 142(1), pp.333~340 (2016), Springer Science and Business Media LLC[DOI]
- David Moher, "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement", PLoS Medicine, 6(7), pp.e1000097~ (2009), Public Library of Science (PLoS)[DOI]
- Soo Young Kim, "Testing a tool for assessing the risk of bias for nonrandomized studies showed moderate reliability and promising validity", Journal of Clinical Epidemiology, 66(4), pp.408~414 (2013), Elsevier BV[DOI]
- Claire C. Conley, "Factors associated with intentions for breast cancer risk management: Does risk group matter?", Psycho-Oncology, 28(5), pp.1119~1126 (2019), Wiley[DOI]
- Siranoush Manoukian, "Risk-reducing surgery in BRCA1", BRCA2 mutation carriers: are there factors associated with the choice?, 2019, pp.28(9), 1871~1878[DOI]
- M. Robyn Andersen, "False-positive screening events and worry influence decisions about surgery among high-risk women", Health Psychology, 38(1), pp.43~52 (2019), American Psychological Association (APA)[DOI]
- Ladd MK, "Predictors of risk-reducing surgery intentions following genetic counseling for hereditary breast and ovarian cancer", Transl Behav Med, 10(2), pp.337~346 (2020)[DOI]
- Angie Tong, "Intentions for risk-reducing surgery among high-risk women referred for BRCA1", BRCA2 genetic counseling, 2015, pp.24(1), 33~39[DOI]
- Jessica E. van der Aa, "The effect of personal medical history and family history of cancer on the uptake of risk-reducing salpingo-oophorectomy", Familial Cancer, 14(4), pp.539~544 (2015), Springer Science and Business Media LLC[DOI]
- R Manchanda, "Factors influencing uptake and timing of risk reducing salpingo-oophorectomy in women at risk of familial ovarian cancer: a competing risk time to event analysis", BJOG: An International Journal of Obstetrics & Gynaecology, 119(5), pp.527~536 (2012), Wiley[DOI]
- L Sidon, "Uptake of risk-reducing salpingo-oophorectomy in women carrying a BRCA1 or BRCA2 mutation: evidence for lower uptake in women affected by breast cancer and older women", British Journal of Cancer, 106(4), pp.775~779 (2012), Springer Science and Business Media LLC[DOI]
- Claire Julian-Reynier, "Cancer risk management strategies and perceptions of unaffected women 5 years after predictive genetic testing for BRCA1", 2 mutations, 2011, pp.19(5), 500~506[DOI]
- A-B Skytte, "Risk-reducing mastectomy and salpingo-oophorectomy in unaffected BRCA mutation carriers: uptake and timing", Clinical Genetics, 77(4), pp.342~349 (2010), Wiley[DOI]
- Mary S. Beattie, "Uptake, time course, and predictors of risk-reducing surgeries in BRCA carriers", Genetic Testing and Molecular Biomarkers, 13(1), pp.51~56 (2009), Mary Ann Liebert Inc[DOI]
- Tara M. Friebel, "Bilateral Prophylactic Oophorectomy and Bilateral Prophylactic Mastectomy in a Prospective Cohort of Unaffected BRCA1 and BRCA2 Mutation Carriers", Clinical Breast Cancer, 7(11), pp.875~882 (2007), Elsevier BV[DOI]
- Joanna B. Madalinska, "Predictors of prophylactic bilateral salpingo-oophorectomy compared with gynecologic screening use in BRCA1", 2 mutation carriers, 2007, pp.25(3), 301~307[DOI]
- Vardit Kram, "Acceptance of Preventive Surgeries by Israeli Women Who had Undergone BRCA Testing", Familial Cancer, 5(4), pp.327~335 (2006), Springer Science and Business Media LLC[DOI]
- Erna Claes, "Surveillance Behavior and Prophylactic Surgery After Predictive Testing for Hereditary Breast", Ovarian Cancer, 2005, pp.31(3), 93~106[DOI]
- Marc D. Schwartz, "Bilateral prophylactic oophorectomy and ovarian cancer screening following BRCA1", BRCA2 mutation testing, 2003, pp.21(21), 4034~4041[DOI]
- Carolyn Y Fang, "Psychosocial correlates of intention to undergo prophylactic oophorectomy among women with a family history of ovarian cancer", Preventive Medicine, 37(5), pp.424~431 (2003), Elsevier BV[DOI]
- Karen E. Hurley, "Anxiety", Uncertainty Reduction as a Motivation for Interest in Prophylactic Oophorectomy in Women with a Family History of Ovarian Cancer, 2001, pp.10(2), 189~199[DOI]
- Alison Fry, "Deciding about Prophylactic Oophorectomy: What Is Important to Women at Increased Risk of Ovarian Cancer?", Preventive Medicine, 33(6), pp.578~585 (2001), Elsevier BV[DOI]
- Bettina Meiser, "Attitudes toward Prophylactic Oophorectomy and Screening Utilization in Women at Increased Risk of Developing Hereditary Breast", Ovarian Cancer, 1999, pp.75(1), 122~129[DOI]
- Rachael Glassey, "Decision making, psychological wellbeing and psychosocial outcomes for high risk women who choose to undergo bilateral prophylactic mastectomy – A review of the literature", The Breast, 28, pp.130~135 (2016), Elsevier BV[DOI]
- Brittany Ager, "Contralateral prophylactic mastectomy (CPM): A systematic review of patient reported factors and psychological predictors influencing choice and satisfaction", The Breast, 28, pp.107~120 (2016), Elsevier BV[DOI]
- Shirley Sun, "Factors shaping at‐risk individuals’ decisions to undergo genetic testing for cancer in Asia", Health & Social Care in the Community, 28(5), pp.1569~1577 (2020), Wiley[DOI]
- Iman Haroun, "Reasons for risk-reducing mastectomy versus MRI-screening in a cohort of women at high hereditary risk of breast cancer", The Breast, 20(3), pp.254~258 (2011), Elsevier BV[DOI]
