솔젤법에 의한 다이옵사이드 생체 세라믹의 표면코팅 및 지르코니아 기판의 생체활성 증진
Bioactivity enhancement of zirconia substrate by surface coating of diopside bioceramics using sol-gel method
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다이옵사이드(CaMgSi₂O₆)는 생체활성이 높을 뿐만 아니라 우수한 기계적 성질도 보유한 물질로 알려져 있다. 본 연구에서는 지르코니아 세라믹스의 생체활성을 향상시키기 위하여 지르코니아 기판 표면에 다이옵사이드를 솔젤법으로코팅하고 in vitro 시험을 통해 지르코니아 기판의 생체활성 증진을 고찰하였다. 코팅용 다이옵사이드 솔은 Ca(NO₃)₂·4H₂O, MgCl₂·6H₂O and Si(OC₂H₅)₄를 각각의 몰비로 에탄올에 용해한 후 가수분해시켜 제조하였다. 다이옵사이드 코팅에 의한 생체활성 증진을 고찰하기 위하여 SBF 용액 내에서 in vitro 시험을 진행하였는데, 침적초기에는 주로 코팅층 다이옵사이드 입자들의 표면용해가 관찰되었고, 새로운 하이드록시아파타이트 입자의 석출은 14일 침적시편에서 주로 관찰되었다. In vitro 시험 시 SBF(Simulated Body Fluid) 용액에 대한 다이옵사이드 코팅층의 용해와 기판 표면에 석출되는 하이드록시아파타이트 층의 양과 형태는 코팅횟수와 코팅층 두께에 의존하였다.
Abstract
Diopside (CaMgSi₂O₆) is known to have high bioactivity as well as excellent mechanical properties. In this study, we tried to improve the bioactivity of zirconia ceramics by surface coating of diopside and its bioactivity was investigated through an in vitro test. Surface coating on zirconia substrate was prepared by sol-gel method using a diopside sol which was prepared by dissolving Ca(NO₃)₂·4H₂O, MgCl₂·6H₂O and Si(OC₂H₅)₄ in ethanol with a fixed molar ratio andthen hydrolysis. To examine the bioactivity of diopside coating, we examined the surface dissolution and the precipitation of new hydroxyapatite particles through in vitro test in SBF (Simulated Body Fluid) solution. Dense and thick diopside coating layers could be fabricated on zirconia substrate by sol-gel method. Also, we confirmed that they contained high bioactivity from the in vitro test, indicated the precipitation of hydroxyapatite particles after the 14 days immersion in SBF solution. In addition, we checked that the bioactivity of diopside coated layers was dependent on the repeated coating cycle and coating thickness.
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