Hydration Effects of Water or Sports Beverages on the Peripheral Markers of Blood-Brain Barrier Integrity During Endurance Exercises at High Ambient Temperatures
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This study aimed to investigate the fluid replacement effects of water or sports beverages on the peripheral markers of blood-brain barrier (BBB) integrity during endurance exercises at high ambient temperatures. Six healthy males were recruited and completed running trials in the following four conditions: 1) thermoneutral temperature at 18℃ (trial 18), 2) high ambient temperature at 32℃ without fluid replacement (trial 32), 3) high ambient temperature at 32℃ with water replacement (trial 32+W), and 4) high ambient temperature at 32℃ with sports beverage replacement (trial 32+S). Blood samples were collected pre-exercise, post-exercise, and 1-h post-exercise for each condition. In trial 32, hematocrit levels were significantly increased post-exercise than pre-exercise (p < 0.05). In all trials, the S100β levels were significantly increased post-exercise compared to pre-exercise (p < 0.05). Furthermore, the S100β levels were significantly decreased in all trials 1-h post-exercise than post-exercise (p < 0.05), and these levels were significantly higher 1-h post-exercise in trial 32 than in other trials (p < 0.05). In all trials, ammonia levels were significantly higher post-exercise than pre-exercise (p < 0.05). These results suggested that exercises at high ambient temperatures could damage the BBB more than exercises at thermoneutral temperatures. Additionally, water or sports beverage hydration during acute exercises at high ambient temperatures can effectively reduce BBB damage caused by exercise and thermal stress.
Abstract
This study aimed to investigate the fluid replacement effects of water or sports beverages on the peripheral markers of blood-brain barrier (BBB) integrity during endurance exercises at high ambient temperatures. Six healthy males were recruited and completed running trials in the following four conditions: 1) thermoneutral temperature at 18℃ (trial 18), 2) high ambient temperature at 32℃ without fluid replacement (trial 32), 3) high ambient temperature at 32℃ with water replacement (trial 32+W), and 4) high ambient temperature at 32℃ with sports beverage replacement (trial 32+S). Blood samples were collected pre-exercise, post-exercise, and 1-h post-exercise for each condition. In trial 32, hematocrit levels were significantly increased post-exercise than pre-exercise (p < 0.05). In all trials, the S100β levels were significantly increased post-exercise compared to pre-exercise (p < 0.05). Furthermore, the S100β levels were significantly decreased in all trials 1-h post-exercise than post-exercise (p < 0.05), and these levels were significantly higher 1-h post-exercise in trial 32 than in other trials (p < 0.05). In all trials, ammonia levels were significantly higher post-exercise than pre-exercise (p < 0.05). These results suggested that exercises at high ambient temperatures could damage the BBB more than exercises at thermoneutral temperatures. Additionally, water or sports beverage hydration during acute exercises at high ambient temperatures can effectively reduce BBB damage caused by exercise and thermal stress.
참고문헌 (37)
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