비뇨기과적 수술 후 도뇨관 유치 환자에 있어서 국소 항생제 연고 도포의 효용성
Effectiveness of Topical Ofloxacin Ointment for Genitourinary Post-Operative Patients with Urinary Catheterization
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Purpose: Catheter associated urinary tract infection and discomfort is common in patients with an indwelling urinary catheter. We investigated the effectiveness of prophylactic topical antibiotic ointment for genitourinary post-operative patients with a urinary catheter.Materials and Methods: We investigated 112 inpatients between March 2013 and October 2013, who had an indwelling urinary catheter ≥24 hours after a genitourinary operation in our institution from medical records. Among 112 patients, 59 patients applied ofloxacin ointment to urethral meatus around the indwelling catheter twice a day (ointment group: 52.7%) and 53 patients did not (non-ointment group: 47.3%). All patients were examined by urine analysis and urine culture before the operation, urethral sweep culture after catheter removal, and severity of pain was recorded as visual analogue scale (VAS) score while having an indwelling urinary catheter.Results: Mean duration of urinary catheter of both groups did not differ statistically (3.08±2.19 day, 2.91±2.25 day). Patients with pyuria detected at pre-operative urinalysis were 22.1% vs. 15.1%, pre-operative urine culture positive were 6.8% vs. 9.4%, urethra meatal culture positive after urethral catheter removal were 16.9% vs. 13.2%, respectively, and all results showed no significant differences between two groups. VAS scores of the ointment group (3.52±1.66) while having an indwelling urinary catheter were significantly lower than those of the non-ointment group (5.61±1.75) (p<0.001).Conclusions: Application of topical antibiotic ointment for genitourinary post-operative patients with urinary catheter had no benefit in reducing growth of urethral microorganisms, but it may decrease pain from an indwelling urinary catheter.
Abstract
Purpose: Catheter associated urinary tract infection and discomfort is common in patients with an indwelling urinary catheter. We investigated the effectiveness of prophylactic topical antibiotic ointment for genitourinary post-operative patients with a urinary catheter.Materials and Methods: We investigated 112 inpatients between March 2013 and October 2013, who had an indwelling urinary catheter ≥24 hours after a genitourinary operation in our institution from medical records. Among 112 patients, 59 patients applied ofloxacin ointment to urethral meatus around the indwelling catheter twice a day (ointment group: 52.7%) and 53 patients did not (non-ointment group: 47.3%). All patients were examined by urine analysis and urine culture before the operation, urethral sweep culture after catheter removal, and severity of pain was recorded as visual analogue scale (VAS) score while having an indwelling urinary catheter.Results: Mean duration of urinary catheter of both groups did not differ statistically (3.08±2.19 day, 2.91±2.25 day). Patients with pyuria detected at pre-operative urinalysis were 22.1% vs. 15.1%, pre-operative urine culture positive were 6.8% vs. 9.4%, urethra meatal culture positive after urethral catheter removal were 16.9% vs. 13.2%, respectively, and all results showed no significant differences between two groups. VAS scores of the ointment group (3.52±1.66) while having an indwelling urinary catheter were significantly lower than those of the non-ointment group (5.61±1.75) (p<0.001).Conclusions: Application of topical antibiotic ointment for genitourinary post-operative patients with urinary catheter had no benefit in reducing growth of urethral microorganisms, but it may decrease pain from an indwelling urinary catheter.
참고문헌 (25)
- Yim SH, "Treatment and prevention of catheter-associated urinary tract infections", Korean J Urogenit Tract Infect Inflamm, 4, pp.159~169 (2009)
- Yoo JY, "Preliminary study on protective effect of urovaxomⓇ in the longterm urinary catheterized patients", Korean J Urogenit Tract Infect Inflamm, 3, pp.95~98 (2008)
- Warren JW, "A prospective microbiologic study of bacteriuria in patients with chronic indwelling urethral catheters", J Infect Dis, 146, pp.719~723 (1982)
- Hooton TM, "Infectious Diseases Society of America. Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America", Clin Infect Dis, 50, pp.625~663 (2010)
- Yoon H, "European and Asian guidelines on management and prevention of catheter-associated urinary tract infections", Korean J Urogenit Tract Infect Inflamm, 3, pp.137~147 (2008)
- 양승옥, "카테터연관 요로감염", Urogenital Tract Infection, 8(2), pp.73~82 (2013), 대한요로생식기감염학회
- Classen DC, "Prevention of catheter-associated bacteriuria: clinical trial of methods to block three known pathways of infection", Am J Infect Control, 19, pp.136~142 (1991)
- Burke JP, "Prevention of catheter-associated urinary tract infections. Efficacy of daily meatal care regimens", Am J Med, 70, pp.655~658 (1981)
- Tenke P, "European and Asian guidelines on management and prevention of catheter-associated urinary tract infections", Int J Antimicrob Agents, 31(Suppl 1), pp.S68~S78 (2008)
- Platt R, "Risk factors for nosocomial urinary tract infection", Am J Epidemiol, 124, pp.977~985 (1986)
- Warren JW, "Nosocomial and health care associated infections in urology", pp.153~176 (2001), Health Publications Ltd
- Sedor J, "Hospital-acquired urinary tract infections associated with the indwelling catheter", Urol Clin North Am, 26, pp.821~828 (1999)
- Stamm WE, "Urinary tract infections: from pathogenesis to treatment", J Infect Dis, 159, pp.400~406 (1989)
- Warren JW, "Catheter-associated urinary tract infections", Int J Antimicrob Agents, 17, pp.299~303 (2001)
- Steward DK, "Failure of the urinalysis and quantitative urine culture in diagnosing symptomatic urinary tract infections in patients with long-term urinary catheters", Am J Infect Control, 13, pp.154~160 (1985)
- Tambyah PA, "Catheter-associated urinary tract infection is rarely symptomatic: a prospective study of 1,497 catheterized patients", Arch Intern Med, 160, pp.678~682 (2000)
- Bergqvist D, "The relevance of urinary sampling methods in patients with indwelling Foley catheters", Br J Urol, 52, pp.92~95 (1980)
- Ibrahim AI, "Hospital acquired pre-prostatectomy bacteriuria: risk factors and implications", East Afr Med J, 73, pp.107~110 (1996)
- Grabe M, "Host parasite interaction in urinary tract infection", pp.303~306 (1986), University of Göteborg
- Sullivan NM, "Clinical aspects of bacteremia after manipulation of the genitourinary tract", J Infect Dis, 127, pp.49~55 (1973)
- Bregenzer T, "Low risk of bacteremia during catheter replacement in patients with long-term urinary catheters", Arch Intern Med, 157, pp.521~525 (1997)
- Tambyah PA, "Catheter-associated urinary tract infection", Curr Opin Infect Dis, 25, pp.365~370 (2012)
- Patel AR, "Lidocaine 2% gel versus plain lubricating gel for pain reduction during flexible cystoscopy: a meta-analysis of prospective, randomized, controlled trials", J Urol, 179, pp.986~990 (2008)
- Ho KJ, "Lignocaine gel: does it cause urethral pain rather than prevent it", Eur Urol, 43, pp.194~196 (2003)
- Siderias J, "Comparison of topical anesthetics and lubricants prior to urethral catheterization in males: arandomized controlled trial", Acad Emerg Med, 11, pp.703~706 (2004)
