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Male Human Papilloma Virus Infections: How to Prepare for Vaccination Strategies

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초록

Human papillomavirus (HPV) infections are linked to benign and malignant urogenital conditions, with varying risks associated with different HPV genotypes. Genital warts, mainly caused by low-risk HPV types, have seen a recent surge in incidence, leading to escalating medical costs. While vaccines like Cervarix and Gardasil target females, the exclusion of Gardasil 9 raises questions about gender-neutral vaccination strategies. Studies highlight potential cost savings through male HPV vaccination but note the rising prices of HPV vaccines, particularly Gardasil 9. Recent findings underscore HPV's expansion into nasopharyngeal cancer, urging the introduction of male HPV vaccination programs. However, the increasing vaccine costs raise concerns about accessibility and affordability. Regulatory bodies and healthcare stakeholders must address these challenges to ensure equitable HPV prevention and control measures. Efforts to control vaccine pricing and promote comprehensive immunization strategies are crucial in mitigating the growing burden of HPV-related diseases.

Abstract

Human papillomavirus (HPV) infections are linked to benign and malignant urogenital conditions, with varying risks associated with different HPV genotypes. Genital warts, mainly caused by low-risk HPV types, have seen a recent surge in incidence, leading to escalating medical costs. While vaccines like Cervarix and Gardasil target females, the exclusion of Gardasil 9 raises questions about gender-neutral vaccination strategies. Studies highlight potential cost savings through male HPV vaccination but note the rising prices of HPV vaccines, particularly Gardasil 9. Recent findings underscore HPV's expansion into nasopharyngeal cancer, urging the introduction of male HPV vaccination programs. However, the increasing vaccine costs raise concerns about accessibility and affordability. Regulatory bodies and healthcare stakeholders must address these challenges to ensure equitable HPV prevention and control measures. Efforts to control vaccine pricing and promote comprehensive immunization strategies are crucial in mitigating the growing burden of HPV-related diseases.

참고문헌 (4)

  1. Kombe Kombe AJ, "Epidemiology and burden of human papillomavirus and related diseases, molecular pathogenesis, and vaccine evaluation", Front Public Health, 8, pp.552028~ (2021)
  2. Li Y, "Human papillomavirus-related cancers", Adv Exp Med Biol, 1018, pp.23~34 (2017)
  3. Kim EJ, "Trends of genital wart in Korea according to treatment method classification : big data analysis of health care in 2010-2019", Investig Clin Urol, 64, pp.56~65 (2023)
  4. Kim Y, "Petition filed against MSD’s price hike on cervical cancer vaccine", Korea Biomedical Review (2021)

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